Interdisciplinary Journal of Acute Care

Interdisciplinary Journal of Acute Care

The Effects of Mentalization-Based Therapy and Attachment-Based Therapy on Positive and Negative Affect Regulation in Individuals with Borderline Personality Disorder

Document Type : Research

Authors
1 Health Psychology, Kish International Branch, Islamic Azad University, Kish, Iran.
2 Department of Educational Sciences and Educational Management, Mashhad Branch, Islamic Azad University, Mashhad, Iran
3 Department of Health Psychology, Karaj Branch, Islamic Azad University, Karaj, Iran.
Abstract
This study compared mentalization-based therapy (MBT) and attachment-based therapy (ABT) for positive and negative affect in individuals with borderline personality disorder (BPD). A quasi-experimental pretest-posttest-follow-up design included 45 participants aged 18-35 years with BPD, randomly assigned to MBT (n=15), ABT (n=15), or a control condition (n=15). The interventions comprised 10 weekly two-hour sessions delivered by trained therapists. The Borderline Symptom List and Positive and Negative Affect Schedule assessed outcomes at pre-test, post-test, and 2-month follow-up. Mixed-model analysis of variance revealed significant main effects of time on positive affect (F=703.44, p<0.001) and negative affect (F=1422.68, p<0.001). The time × group interactions were significant for both outcomes (positive affect: η²ₚ = 0.84; negative affect: η²ₚ = 0.85), with large effect sizes. Both MBT and ABT significantly improved positive and negative affect relative to the control condition. Importantly, MBT demonstrated superior effectiveness in enhancing positive affect. Treatment gains were maintained during the 2-month follow-up period. Both MBT and ABT effectively improve affect regulation in BPD through distinct mechanistic pathways: MBT via enhanced mentalizing capacity and ABT via improved relational security. MBT's superiority in positive affect suggests a particular clinical benefit for subjective well-being. Despite these promising findings, the modest sample size limits the statistical power and generalizability of the results. Larger multicenter randomized controlled trials are recommended to confirm these findings and establish optimal treatment strategies for individuals with BPD.
Keywords

1. Leichsenring F, Fonagy P, Heim N, Kernberg OF, Leweke F, Luyten P, Salzer S, Spitzer C, Steinert C. Borderline personality disorder: a comprehensive review of diagnosis and clinical presentation, etiology, treatment, and current controversies. World Psychiatry. 2024 Feb;23(1):4-25. https://doi.org/10.1002/wps.21156  
2. Lieb K, Zanarini MC, Schmahl C, Linehan MM, Bohus M. Borderline personality disorder. Lancet. 2004;364(9432):453-61. https://doi.org/10.1016/S0140-6736(04)16770-6  
3. D'Aurizio G, Di Stefano R, Socci V, Rossi A, Barlattani T, Pacitti F, et al. The role of emotional instability in borderline personality disorder: a systematic review. Annals of General Psychiatry. 2023;22(1):9. https://doi.org/10.1186/s12991-023-00439-0  
4. Tomko RL, Lane SP, Pronove LM, Treloar HR, Brown WC, Solhan MB, et al. Undifferentiated negative affect and impulsivity in borderline personality and depressive disorders: a momentary perspectiveJournal of Psychopathology and Clinical Science. 2015;124(3):740-53. https://doi.org/10.1037/abn0000064  
5. Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. Journal of Personality and Social Psychology. 1988;54(6):1063-70. https://doi.org/10.1037/0022-3514.54.6.1063  
6. Stellar JE, John-Henderson N, Anderson CL, Gordon AM, McNeil GD, Keltner D. Positive affect and markers of inflammation: discrete positive emotions predict lower levels of inflammatory cytokines. Emotion. 2015;15(1):129-35. https://doi.org/10.1037/emo0000031  
7. Fonagy P, Bateman AW, Luyten P. Introduction and overview. In: Bateman AW, Fonagy P, editors. Handbook of mentalizing in mental health practice. Arlington: American Psychiatric Publishing; 2012. p. 3-42.
8. Fonagy P, Campbell C. Bad blood revisited: attachment and psychoanalysis. British Journal of Psychotherapy. 2015;31(2):229-50. https://doi.org/10.1111/bjp.12136  
9. Fonagy P, Bateman A. Mentalization-based treatment for personality disorders: a practical guide. Oxford: Oxford University Press; 2016.
10. Juul S, Lunn S, Poulsen S, Sّrensen P, Salimi M, Jakobsen JC, et al. Short-term versus long-term mentalization-based therapy for outpatients with subthreshold or diagnosed borderline personality disorder: a protocol for a randomized clinical trial. Trials. 2019;20(1):196. https://doi.org/10.1186/s13063-019-3306-7  
11. Brisch KH. Treating attachment disorders: from theory to therapy. New York: Guilford Publications; 2002.
12. Fonagy, P. Affect regulation, mentalization, and the development of the self. London: Routledge, 2018.
13. Haj Mohammadhosseini T, Mirzahosseini H, Zargham Hajebi M. Comparison of the effectiveness of mentalization therapy and affect phobia therapy on reducing symptoms of borderline personality disorder and depression in women. Journal of Mashhad University of Medical Sciences. 2021;64(1):2631-41. https://doi.org/10.22038/mjms.2021.19026  
14. Beck E, Bo S, Jّrgensen MS, Gondan M, Poulsen S, Storebّ OJ, et al. Mentalization-based treatment in groups for adolescents with borderline personality disorder: a randomized controlled trial. Journal of Child Psychology and Psychiatry. 2020;61(5):594-604. https://doi.org/10.1111/jcpp.13152  
15. Beck E, Bo S, Jّrgensen MS, Gondan M, Poulsen S, Storebّ OJ, Fjellerad Andersen C, Folmo E, Sharp C, Pedersen J, Simonsen E. Mentalization-based treatment in groups for adolescents with borderline personality disorder: a randomized controlled trial Journal of Child Psychology and Psychiatry. 2020;61(5):594-604. https://doi.org/10.1111/jcpp.13152  
16. Van Vlierberghe L, Diamond G, Bosmans G. Middle childhood attachment-based family therapy: theory and model description. Family Process. 2023;62(3):1040-54. https://doi.org/10.1111/famp.12787  
17. Hoffman KT, Marvin RS, Cooper G, Powell B. Changing toddlers' and preschoolers' attachment classification: the circle of security intervention. Journal of Clinical Psychology. 2006;47(6):1017-26. https://doi.org/10.1037/0022-0167.47.6.1017  
18. Tahmasbian H, Ahmadi V, Mami S. Comparison of the effectiveness of attachment therapy with motivational therapy in reducing relapse, craving, and maintaining abstinence in patients with borderline personality disorder dependent on substances. Knowledge & Research in Applied Psychology. 2022;23(2):106-22. [Persian]
19. Keivanloo A, Saremi AA, Nouri R. Effectiveness of attachment-based therapy on attachment style, emotion regulation difficulties, and treatment adherence in patients with chronic gastric ulcers. Journal of Mashhad University of Medical Sciences. 2023;66(3):476-92. [Persian]
20. Collado-Navarro C, Navarro-Gil M, Pérez-Aranda A, Lَpez-del-Hoyo Y, Garcia-Campayo J, Montero-Marin J. Effectiveness of mindfulness-based stress reduction and attachment-based compassion therapy for the treatment of depressive, anxious, and adjustment disorders in mental health settings: a randomized controlled trial. Depression Anxiety. 2021;38(11):1138-51. https://doi.org/10.1002/da.23198  
21. Ibrahim M, King A, Levy S, Russon J, Diamond G. Increased family cohesion mediates therapist adherence to the attachment task and depression outcomes in attachment-based family therapy. Journal of Contemporary Psychotherapy. 2022;52(4):303-10.  https://doi.org/10.1007/s10879-022-09539-6  
22. Cohen, J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale: Lawrence Erlbaum Associates; 1988.
23. Keppel G, Wickens TD. Design and analysis: a researcher's handbook. 4th ed. New York: Pearson Prentice Hall; 2004.
24. Bohus M, Limberger MF, Frank U, Chapman AL, Kühler T, Stieglitz RD. Psychometric properties of the borderline symptom list (BSL). Psychopathology. 2007;40(2):126-32. https://doi.org/10.1159/000098493  
25. Bohus M, Kleindienst N, Limberger MF, Stieglitz RD, Domsalla M, Chapman AL, et al. The short version of the borderline symptom list (BSL-23): development and initial data on psychometric properties. Psychopathology. 2009;42(1):32-9. https://doi.org/10.1159/000173701 
26. Kleindienst N, Jungkunz M, Bohus M. A proposed severity classification of borderline symptoms using the borderline symptom list (BSL-23). Borderline Personality Disorder and Emotion Dysregulation. 2020;7:11. https://doi.org/10.1186/s40479-020-00126-6  
27. Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. Journal of Personality and Social Psychology. 1988;54(6):1063-70.  https://doi.org/10.1037/0022-3514.54.6.1063  
28. Crawford JR, Henry JD. The positive and negative affect schedule (PANAS): construct validity, measurement properties and normative data in a large non-clinical sample. British Journal of Clinical Psychology. 2004;43(Pt 3):245-65.  https://doi.org/10.1348/0144665031752934  
29. Jahanbakhsh M, Amiri S, Molavi H, Bahadori MH. The relationship of attachment problems in girls with attachment style of mothers. Journal of Clinical Psychology. 2010;2(3):15-23.
30. Fonagy P, Target M. Attachment and reflective function: their role in self-organization. Development and Psychopathology. 1997;9(4):679-700. https://doi.org/10.1017/s0954579497001399   
31. Stoffers-Winterling JM, Storebّ OJ, Kongerslev MT, Faltinsen E, Todorovac A, et al. Psychotherapies for borderline personality disorder: a focused systematic review and meta-analysis. British Journal of Clinical Psychology. 2022;221(3):538-52. https://doi.org/10.1192/bjp.2021.204  
32. Navarro-Gil M, Lَpez-del-Hoyo Y, Modrego-Alarcَn M, Montero-Marیn J, Van Gordon W, Shonin E, et al. Effects of attachment-based compassion therapy (ABCT) on self-compassion and attachment style in healthy people. Mindfulness. 2020;11:51-62. https://doi.org/10.1007/s12671-019-0253-x  
33. Fonagy P, Bateman AW. Mechanisms of change in mentalization-based treatment of borderline personality disorder. Journal of Clinical Psychology. 2006;62(4):411-30. 
https://doi.org/10.1002/jclp.20241  
34. Daros AR, Williams GE. A meta-analysis and systematic review of emotion-regulation strategies in borderline personality disorder. Harvard Review of Psychiatry. 2019;27(4):217-32. https://doi.org/10.1097/HRP.0000000000000212  
Volume 6, Issue 2
December 2025
Pages 92-100

  • Receive Date 02 November 2025
  • Revise Date 14 November 2025
  • Accept Date 01 December 2025